ILTS Insights: Pediatric liver transplantation for metabolic liver disease

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November 23, 2021

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  • Discuss the indication and timing of liver transplantation for metabolic liver disease in children
  • Discuss the indication and post-transplant management of PFIC-1


  • Introduction
  • Liver Transplantation for Metabolic liver disease (George V. Mazariegos)
  • Liver transplantation for PFIC-1 (Ciğdem Arıkan)
  • Q&A moderated by Manuel Rodriguez-Davalos and Nam-Joon Yi


Sponsored by:


Bridge to Life is a leading supplier of preservation solutions globally with a focus on innovation in organ preservation and machine perfusion. Through a strong focus on collaboration with surgeons and transplant professionals, Bridge to Life continues to explore emerging science and preservation technologies.

Speaker Details

George V. Mazariegos


George V. Mazariegos, MD, FACS, specializes in pediatric transplant surgery at UPMC Children’s Hospital of Pittsburgh. He is certified by the American College of Surgeons and is chief of Pediatric Transplantation at UPMC while holding the title of Jamie Lee Curtis Chair in Transplantation Surgery. He received his medical degree from Northwestern University Medical School, completed his residency at Michigan State University, followed by fellowships at UPMC in critical care medicine, and the Thomas E. Starzl fellowship in transplantation, hepatic, and multivisceral transplantation. Dr. Mazariegos’ clinical interests include treatment of pediatric patients who have liver and intestinal disease that require transplantation or hepatobiliary surgery.

Ciğdem Arıkan


Ciğdem Arıkan, MD, completed her high school education in Istanbul Erenkoy High school in 1995 and then graduated from İstanbul University Medical Faculty. She got her degree on children’s health and diseases in Marmara University İn the year 2001, the same year in Ege University she started Child Gastroenterology, Hepatology and nutrition science as a side branch and graduated in the year 2005. Between the years 2005-2006 she worked in the Texas Childrens Hospital Liver research center. Dr. Arıkan won 6 scientific awards, 2 abroad research scholarships, 62 international research articles and Her h-index is 22.

Manuel Rodriguez-Davalos


Manuel Rodriguez-Davalos, MD, Medical Director, Living Donor Liver Transplantation Program, Intermountain Medical Center and Surgical Director, Pediatric Liver Transplantation, Primary Children’s Hospital, Intermountain Healthcare. Dr. Rodriguez-Davalos has previously held positions in transplant at Yale University, Mount Sinai Medical Center and New York Medical College.He is committed to innovation and collaboration to improve organ donation, transplantation and allocation systems to benefit those in need, especially children. He has particular interest in living donor transplants, organ allocation, and portal hypertension.

Nam-Joon Yi


Nam-Joon Yi, MD, PhD, is currently a professor of Surgery at Seoul National University College of Medicine. She obtained her MD and PhD degree s at the Ewha Womans University in Seoul, Korea in 1996 and 2004. Since 2002, she started her clinical fellowship and has dedicated to set up a living donor liver transplantation program in H BP Surgery division of Seoul National University Hospital. She has special expertise in living donor and pediatric liver transplantation. Her research interests include micro chimerism of the liver graft in the pediatric transplantation, regeneration of the small for size graft, and operational tolerance in liver transplantation.

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