ILTS Insights – Critical Issues in Pediatric Liver Transplantation: Let’s Talk More

Our experts will discuss the current status of transplant tolerance and hepatoblastoma state-of-the-art. Where do we stand and how far we can achieve?



Critical Issues in Pediatric Liver Transplantation: Let’s Talk More


February 16, 2023

14:00 – 17:00 CET


In collaboration with the Korean Association of Hepato-Biliary Pancreatic Surgery (KAHBPS).




Current status of transplant tolerance and hepatoblastoma state-of-the-art. Where do we stand and how far we can achieve?



  • Biomarkers in operational tolerance, experience, and trial
  • Hepatoblastoma, resection, or transplantation?



Part 1: Current Status of Transplant Tolerance

  • Biomarkers in operational tolerance – Alberto Sanchez-Fueyo
  • Prospective tolerance trials- status – Sandy Feng
  • LDLT based experience – Mureo Kasahara
  • Q&A
  • Closing

Part 2: Hepatoblastoma State-of-the-art

  • Extreme resection or Transplant – Jean Ville de Goyet
  • Status of SIOPEL: East perspective – Tomoro Hishiki
  • Status of SIOPEL: West perspective – Greg M. Tiao
  • The oncologists’ perspective – Kyung-Nam Koh
  • Q&A
  • Closing

Speaker Details

Alberto Sanchez-Fueyo


Professor of Hepatology, Academic Head of the Institute of Liver Studies at King’s College London, and Honorary Transplant Hepatology Consultant at King’s College Hospital. His research has focused on understanding the mechanisms of immunological tolerance in transplantation and developing novel immunomodulatory therapies, for which he has received funding from MRC, NIHR, NIH and EU, among others. Additional research interests include the generation of genetically engineered regulatory T cells for immunotherapeutic purposes, which is now being pursued in collaboration with Quell Therapeutics, a King’s spin-off biotech which he contributed to found in 2019.

Sandy Feng


As Professor of Surgery and Director of the Abdominal Transplant Fellowship Program at UCSF, Dr. Sandy Feng performs liver, kidney and pancreas transplants and teaches surgical fellows, residents, and medical students. She received a doctorate in molecular biology from Cambridge University with her Marshall Scholarship and earned her medical degree at Stanford University School of Medicine. She then completed general surgery residency at the Brigham and Women's Hospital in Boston and a transplant fellowship at the University of California, San Francisco.

Mureo Kasahara


Dr. Mureo Kasahara started his professional career in HPB and transplant surgery at Kyoto University School of Medicine from 1996. He also served as a fellow at the Liver Transplant Surgery Service in King’s College Hospital in London, UK in 2002. He is now the Head of Transplant Center and Executive Director in the internationally renowned National Center for Child Health and Development in Tokyo, Japan from April 2022. Since 1996, he has been performing a largest number of living related pediatric liver transplants (1500 cases) for children from all over the world.

George Mazariegos


Chief, Pediatric Transplantation, Professor of Surgery and Critical Care, University of Pittsburgh School of Medicine

Nam-Joon Yi


Director of Transplantation Center of Seoul National University Hospital, Professor of Surgery, Seoul National University College of Medicine

Jean Ville de Goyet


Dr. Ville de Goyet is the Director of the Department for the Treatment and Study of Pediatric Abdominal Diseases and Abdominal Transplantation. He is considered one of the leading experts in pediatric abdominal surgery and liver transplantation, and has performed more than 500 pediatric transplants, with a survival rate of nearly 100% in living donor transplants. Dr. de Ville de Goyet divided his medical training between Paris and Brussels. He arrived in Italy in 2007, where he directed the Department of Pediatric Surgery and Transplantation at the Bambin Gesù Children’s Hospital in Rome, where in the course of 10 years, he created a new pediatric transplant center, achieving exceptional results, obtained in very few centers worldwide. The results include a 7-year survival rate of 96%.

Tomoro Hishiki


Dr. Tomoro Hishiki, M.D., PhD is the Chair of Department of Pediatric Surgery, Chiba University Hospital, Japan. During the last two decades, Dr. Tomoro Hishiki has dedicated himself to clinical trials for hepatoblastoma, being consecutively active in the liver tumor committee of the Japanese Children’s Cancer Group, formally known as JPLT. Throughout this period, as one of the major representatives of the group, he has internationally collaborated with colleagues of the SIOPEL group and the rare tumor committee of COG. He is the current chair of the liver tumor committee.

Greg M. Tiao


Director, Division of General and Thoracic Surgery, Frederick C. Ryckman Chair in Pediatric Surgery, Surgical director of liver transplantation, professor of UC Department of Cincinnati Children’s Hospital, OH, USA Surgery.

Kyung-Nam Koh


Professor, Division of Pediatric Hematology/Oncology, department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Director, Liver Tumor Committee of the Korean Pediatric Hematology-Oncology Group (KPHOG).

Manuel Rodriguez-Davalos


Manuel Rodriguez-Davalos currently works at the Department of Transplant Services, Intermountain Healthcare. He is the Surgical Director for Primary Children's Hospital Liver Transplant program and the Medical Director for Intermountain's Living Donor Liver Transplantation program. Manuel does research in Educational Leadership, Living Donor Liver Transplantation, Split Liver transplantation, Meso-Rex bypass and portal hypertension surgery in children. Their current projects include quality models for safe and efficient work up of living liver donors for children and adult recipients, Hepatoblastoma, Meso-Rex bypass and outcomes for segmental grafts in liver transplantation.

Vidyadhar Mali


Vidyadhar Mali is a Senior Consultant in the Department of Paediatric Surgery and the Surgical Director of the Paediatric Liver and Kidney Transplantation Programmes under the National University Centre for Organ Transplantation at National University Hospital, Singapore. His current interests include the utility of mixed-reality imaging in large-for-size grafts in liver transplantation in infants and the use of different approaches towards tacrolimus dose optimisation. He is actively involved in making recommendations and formulating policies as a member of the "Liver Transplant Subcommittee" and workgroups on "Training and Credentialing" and "Education, Research and Innovation" within the National Liver Transplant Programme under the Ministry of Health, Singapore.

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